SYTL3

Across TCGA cell cohorts, SYTL3 mutation is significantly associated with the RNA expression of many other genes, with 555 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SYTL3-associated genes across cancer lineages are KIR2DS4, BMP15, and IL20. Each is linked with SYTL3 in more than 1 cancer types. Because this analysis shows association rather than direction, both SYTL3-to-partner and partner-to-SYTL3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KIR2DS4 grouped by SYTL3-low versus SYTL3-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SYTL3→partner) and Y-score (partner→SYTL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	KIR2DS4 →	+0.116	+5.029	<.001	.006	3	1
BLOOD_Lymphoma	BMP15 →	+0.021	+4.643	<.001	.005	3	1
BLOOD_Lymphoma	IL20 →	+0.051	+4.350	<.001	.005	3	1
BLOOD_Lymphoma	TRAPPC3L →	+0.112	+4.350	<.001	.005	3	1
BLOOD_Lymphoma	OR51G2 →	+0.010	+5.247	<.001	.001	3	1
BLOOD_Lymphoma	KRTAP3-3 →	+0.045	+5.247	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 555 associations by consensus.

KIR2DS4 by SYTL3 expression — LUNG_SCLC

Explore this box plot interactively →