SYTL2

Across TCGA patient cohorts, SYTL2 protein abundance is significantly associated with the RNA expression of many other genes, with 21,340 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SYTL2-associated genes across cancer lineages are ZBTB7C, STS, and ITGA3. Each is linked with SYTL2 in more than 5 cancer types. Because this analysis shows association rather than direction, both SYTL2-to-partner and partner-to-SYTL2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SYTL2 versus ZBTB7C in BRCA, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SYTL2→partner) and Y-score (partner→SYTL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ZBTB7C →	+1.407	+0.667	<.001	.001	3	6
CCRCC	STS →	+0.676	+0.515	.001	<.001	3	5
LSCC	ITGA3 →	+1.250	+0.408	<.001	.001	3	5
BRCA	BCAS1 →	+2.429	+0.787	<.001	<.001	3	5
LUAD	DHRS7 →	+0.654	+0.698	<.001	<.001	3	5
BRCA	NCAPD2 →	-0.975	-0.880	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,340 associations by consensus.

SYTL2 vs ZBTB7C — BRCA

Explore this scatter interactively →