SYTL1

Across TCGA cell cohorts, SYTL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,264 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible SYTL1-associated GO terms across cancer lineages are Cytotoxic T cell degranulation, Negative regulation of Arp2/3 complex-mediated actin nucleation, and Establishment of epithelial cell apical/basal polarity. Each is linked with SYTL1 in more than 13 cancer types. Because this analysis shows association rather than direction, both SYTL1-to-partner and partner-to-SYTL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytotoxic T cell degranulation grouped by SYTL1-low versus SYTL1-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SYTL1→partner) and Y-score (partner→SYTL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Cytotoxic T cell degranulation →	+0.271	+2.192	<.001	<.001	3	14
OESOPHAGUS	Negative regulation of Arp2/3 complex-mediated actin nucleation →	+0.261	+2.280	<.001	.002	3	11
STOMACH	Establishment of epithelial cell apical/basal polarity →	-0.210	-2.712	.002	.001	3	11
BREAST	Negative regulation of actin nucleation →	+0.189	+2.161	<.001	<.001	3	11
BREAST	Establishment or maintenance of microtubule cytoskeleton polarity →	-0.193	-2.690	<.001	<.001	3	11
BLOOD_Lymphoma	Bundle of His cell-Purkinje myocyte adhesion involved in cell communication →	+1.053	+2.340	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,264 associations by consensus.

Cytotoxic T cell degranulation by SYTL1 expression — BREAST

Explore this box plot interactively →