SYT6

Across TCGA cell cohorts, SYT6 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,217 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SYT6-associated GO terms across cancer lineages are Regulation of double-strand break repair via homologous recombination, Nicotinate metabolic process, and Positive regulation of double-strand break repair. Each is linked with SYT6 in more than 4 cancer types. Because this analysis shows association rather than direction, both SYT6-to-partner and partner-to-SYT6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of double-strand break repair via homologous recombination grouped by SYT6-low versus SYT6-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SYT6→partner) and Y-score (partner→SYT6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Regulation of double-strand break repair via homologous recombination →	+0.059	+1.529	.005	<.001	3	5
LUNG_SCLC	Nicotinate metabolic process →	-0.113	-1.512	.002	<.001	3	5
LUNG_SCLC	Positive regulation of double-strand break repair →	+0.053	+1.427	.006	.002	3	5
LUNG_SCLC	Regulation of DNA repair →	+0.041	+1.397	.004	.001	3	5
BONE	Positive regulation of transmembrane transport →	-0.068	-2.090	<.001	<.001	3	5
UPPER_AERODIGESTIVE_TRACT	Protein folding →	+0.064	+0.023	<.001	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,217 associations by consensus.

Regulation of double-strand break repair via homologous recombination by SYT6 expression — LUNG_SCLC

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