SYT6

Across TCGA cell cohorts, SYT6 protein abundance is significantly associated with the RNA expression of many other genes, with 1,101 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible SYT6-associated genes across cancer lineages are FZD9, ADAP1, and GMCL2. Each is linked with SYT6 in more than 1 cancer types. Because this analysis shows association rather than direction, both SYT6-to-partner and partner-to-SYT6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SYT6 versus FZD9 in SKIN, with a Pearson correlation of -0.57.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SYT6→partner) and Y-score (partner→SYT6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	FZD9 →	-1.272	-1.566	<.001	.005	3	2
CNS	ADAP1 →	-1.532	-2.292	.007	.007	3	2
CNS	GMCL2 →	-0.035	-2.292	<.001	.007	3	2
SKIN	SMPD3 →	+0.272	+1.053	<.001	<.001	2	2
SKIN	POLR1F →	-0.816	-1.376	<.001	.004	3	1
SKIN	H2AZ2 →	-0.742	-1.096	.002	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,101 associations by consensus.

SYT6 vs FZD9 — SKIN

Explore this scatter interactively →