SYT5

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SYT5 protein abundance is significantly associated with the RNA expression of many other genes, with 4,476 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SYT5-associated genes across cancer lineages are SEPTIN3, CELF4, and SYP. Each is linked with SYT5 in more than 1 cancer types. Because this analysis shows association rather than direction, both SYT5-to-partner and partner-to-SYT5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SYT5 versus SEPTIN3 in GBM, with a Pearson correlation of 0.51.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SYT5→partner) and Y-score (partner→SYT5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMSEPTIN3 →+1.033+0.966<.001<.00132
GBMCELF4 →+1.557+1.128<.001<.00132
GBMSYP →+1.381+1.048<.001<.00132
PDACABCC1 →-0.481-0.949.001<.00132
GBMZFR2 →+0.652+0.848<.001<.00132
GBMRUNDC3B →+0.875+0.975<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,476 associations by consensus.

SYT5 vs SEPTIN3 — GBM

Per-sample scatter of SYT5 vs SEPTIN3 in GBM (Pearson r = 0.51).

Explore this scatter interactively →

Exploration