SYT5

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SYT5 protein abundance is significantly associated with the protein abundance of many other proteins, with 13,471 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SYT5-associated proteins across cancer lineages are SYT7, TATDN3, and THSD7A. Each is linked with SYT5 in more than 1 cancer types. Because this analysis shows association rather than direction, both SYT5-to-partner and partner-to-SYT5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SYT5 versus SYT7 in GBM, with a Pearson correlation of 0.94.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SYT5→partner) and Y-score (partner→SYT5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMSYT7 →+1.360+1.275<.001<.00132
GBMTATDN3 →+0.359+0.866<.001<.00132
PDACTHSD7A →+0.641+1.085.001.00132
PDACTTC7B_S677 →+0.500+0.955<.001<.00132
GBMVGF →+1.341+1.035<.001<.00132
GBMCASP8 →-0.348-0.798<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 13,471 associations by consensus.

SYT5 vs SYT7 — GBM

Per-sample scatter of SYT5 vs SYT7 in GBM (Pearson r = 0.94).

Explore this scatter interactively →

Exploration