SYT5

Across TCGA cell cohorts, SYT5 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,986 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible SYT5-associated GO terms across cancer lineages are Negative regulation of syncytium formation by plasma membrane fusion, Regulation of myoblast fusion, and Aerobic electron transport chain. Each is linked with SYT5 in more than 8 cancer types. Because this analysis shows association rather than direction, both SYT5-to-partner and partner-to-SYT5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of syncytium formation by plasma membrane fusion grouped by SYT5-low versus SYT5-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SYT5→partner) and Y-score (partner→SYT5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Negative regulation of syncytium formation by plasma membrane fusion →	+0.082	+0.539	.001	.008	3	9
STOMACH	Regulation of myoblast fusion →	+0.102	+1.650	.009	.009	3	8
BLOOD_Leukemia	Aerobic electron transport chain →	+0.053	+0.537	.002	<.001	3	8
UPPER_AERODIGESTIVE_TRACT	ATP synthesis coupled electron transport →	+0.077	+0.560	<.001	.005	3	8
UPPER_AERODIGESTIVE_TRACT	Mitochondrial ATP synthesis coupled electron transport →	+0.077	+0.560	<.001	.005	3	8
UPPER_AERODIGESTIVE_TRACT	Negative regulation of myoblast fusion →	+0.084	+0.557	<.001	.006	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,986 associations by consensus.

Negative regulation of syncytium formation by plasma membrane fusion by SYT5 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →