Across TCGA patient cohorts, SYT3 protein abundance is significantly associated with the RNA expression of many other genes, with 4,652 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SYT3-associated genes across cancer lineages are SNRPD3, PRODH, and GRK3. Each is linked with SYT3 in more than 1 cancer types. Because this analysis shows association rather than direction, both SYT3-to-partner and partner-to-SYT3 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SYT3→partner) and Y-score (partner→SYT3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SNRPD3 →	+0.331	+0.447	.001	.001	3	1
GBM	PRODH →	+0.728	+0.508	<.001	<.001	3	1
GBM	GRK3 →	+0.392	+0.370	<.001	.001	3	1
GBM	SEZ6L →	+2.199	+0.539	<.001	<.001	3	1
GBM	SNU13 →	+0.270	+0.477	.002	.004	3	1
GBM	SOX10 →	+1.229	+0.571	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,652 associations by consensus.

Exploration

SYT3 survival (RNA) · tumor vs normal (RNA) · all SYT3 data types