SYT17

Across TCGA patient cohorts, SYT17 protein abundance is significantly associated with the RNA expression of many other genes, with 5,008 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SYT17-associated genes across cancer lineages are EPB41L5, TBCK, and ZNF704. Each is linked with SYT17 in more than 2 cancer types. Because this analysis shows association rather than direction, both SYT17-to-partner and partner-to-SYT17 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SYT17 versus EPB41L5 in BRCA, with a Pearson correlation of 0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SYT17→partner) and Y-score (partner→SYT17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	EPB41L5 →	+1.133	+0.449	<.001	.006	3	3
BRCA	TBCK →	+0.849	+0.531	<.001	.006	3	3
BRCA	ZNF704 →	+1.218	+0.765	.002	<.001	3	3
BRCA	IKBKE →	-0.834	-0.671	.003	.002	3	3
BRCA	GGA2 →	+0.668	+0.566	.002	.002	3	2
BRCA	ABCC5 →	+0.929	+0.690	.003	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,008 associations by consensus.

SYT17 vs EPB41L5 — BRCA

Explore this scatter interactively →