SYT17

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SYT17 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,481 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SYT17-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Protein destabilization, and Nuclear-transcribed mRNA poly(A) tail shortening. Each is linked with SYT17 in more than 9 cancer types. Because this analysis shows association rather than direction, both SYT17-to-partner and partner-to-SYT17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by SYT17-low versus SYT17-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SYT17→partner) and Y-score (partner→SYT17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STOMACHNegative regulation of myoblast fusion →+0.108+1.285.007.003310
OVARYProtein destabilization →+0.068+1.195<.001<.00139
SKINNuclear-transcribed mRNA poly(A) tail shortening →+0.072+1.119<.001.00139
LUNG_NSCLC_LUSCFertilization →-0.109-1.935.002.00339
URINARY_TRACTEstablishment of epithelial cell apical/basal polarity →-0.229-1.837.001.00838
UPPER_AERODIGESTIVE_TRACTRegulation of myoblast fusion →+0.086+0.994<.001.00329
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,481 associations by consensus.

Negative regulation of myoblast fusion by SYT17 expression — STOMACH

Box plot of Negative regulation of myoblast fusion in SYT17-low vs SYT17-high samples in STOMACH.

Explore this box plot interactively →

Exploration