SYT16

Across TCGA cell cohorts, SYT16 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,836 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible SYT16-associated GO terms across cancer lineages are Regulation of transforming growth factor beta3 production, Small GTPase-mediated signal transduction, and Establishment of protein localization to membrane. Each is linked with SYT16 in more than 9 cancer types. Because this analysis shows association rather than direction, both SYT16-to-partner and partner-to-SYT16 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of transforming growth factor beta3 production grouped by SYT16-low versus SYT16-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SYT16→partner) and Y-score (partner→SYT16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Regulation of transforming growth factor beta3 production →	+0.258	+1.119	.006	<.001	3	10
OESOPHAGUS	Small GTPase-mediated signal transduction →	+0.055	+1.028	<.001	<.001	3	9
BONE	Establishment of protein localization to membrane →	+0.065	+0.431	.002	.009	3	8
PANCREAS	Cell-substrate junction assembly →	+0.154	+0.670	.001	.008	3	8
BREAST	Positive regulation of myoblast fusion →	+0.233	+0.711	.001	.003	3	8
CNS	Positive regulation of miRNA transcription →	+0.078	+0.486	.001	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,836 associations by consensus.

Regulation of transforming growth factor beta3 production by SYT16 expression — LUNG_NSCLC_LUAD

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