Across TCGA pan-cancer cohorts, SYT14P1 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of SYT14P1’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where SYT14P1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SYT14P1 is over-expressed in tumor, although a few such as HNSC show the opposite, repressed pattern.

LUSC, THCA, and HNSC are the cancer types where SYT14P1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SYT14P1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	All	All	+0.101	.001	5	view →
THCA	Female	II,III,IV	+0.065	.019	5	view →
HNSC	Female	III,IV	−0.091	.043	1	view →
CHOL	Male	All	+0.080	.043	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: SYT14P1 RNA expression & survival · all SYT14P1 data types