SYT10

Across TCGA patient cohorts, SYT10 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,130 significant associations in total. PRAD shows the largest number of these associations.

The most reproducible SYT10-associated GO terms across cancer lineages are Negative regulation of cytoskeleton organization, Cytoskeleton-dependent intracellular transport, and Protein depolymerization. Each is linked with SYT10 in more than 21 cancer types. Because this analysis shows association rather than direction, both SYT10-to-partner and partner-to-SYT10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of cytoskeleton organization grouped by SYT10-low versus SYT10-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SYT10→partner) and Y-score (partner→SYT10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Negative regulation of cytoskeleton organization →	+0.055	+0.091	<.001	<.001	3	22
STAD	Cytoskeleton-dependent intracellular transport →	+0.070	+0.132	<.001	<.001	3	21
SCLC	Protein depolymerization →	+0.074	+0.919	.001	.005	2	22
STAD	Vesicle-mediated transport to the plasma membrane →	+0.069	+0.101	<.001	<.001	3	21
ESCA	Protein-containing complex disassembly →	+0.060	+0.135	<.001	<.001	3	21
STAD	Regulation of cell projection assembly →	+0.059	+0.082	<.001	<.001	3	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,130 associations by consensus.

Negative regulation of cytoskeleton organization by SYT10 expression — STAD

Explore this box plot interactively →