SYT10

Across TCGA cell cohorts, SYT10 RNA expression is significantly associated with the go_rna of many other GO terms, with 513 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible SYT10-associated GO terms across cancer lineages are DNA integrity checkpoint signaling, DNA damage checkpoint signaling, and Regulation of neurotransmitter transport. Each is linked with SYT10 in more than 4 cancer types. Because this analysis shows association rather than direction, both SYT10-to-partner and partner-to-SYT10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA integrity checkpoint signaling grouped by SYT10-low versus SYT10-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SYT10→partner) and Y-score (partner→SYT10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	DNA integrity checkpoint signaling →	+0.038	+1.190	<.001	<.001	3	5
LUNG_SCLC	DNA damage checkpoint signaling →	+0.053	+1.177	<.001	<.001	3	4
LUNG_NSCLC_LUAD	Regulation of neurotransmitter transport →	-0.053	-0.163	<.001	.004	3	4
LUNG_SCLC	Epigenetic regulation of gene expression →	+0.055	+1.376	<.001	<.001	3	4
LUNG_SCLC	miRNA processing →	+0.075	+1.072	.005	.003	3	3
OVARY	Sodium ion transport →	-0.059	-0.244	<.001	.008	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 513 associations by consensus.

DNA integrity checkpoint signaling by SYT10 expression — LUNG_SCLC

Explore this box plot interactively →