SYT10

Across TCGA cell cohorts, SYT10 mutation is significantly associated with the RNA expression of many other genes, with 374 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SYT10-associated genes across cancer lineages are CST9, PLVAP, and H2BC1. Each is linked with SYT10 in more than 1 cancer types. Because this analysis shows association rather than direction, both SYT10-to-partner and partner-to-SYT10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CST9 grouped by SYT10-low versus SYT10-high in BLOOD_Myeloma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SYT10→partner) and Y-score (partner→SYT10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	CST9 →	+0.020	+4.754	<.001	<.001	3	2
SKIN	PLVAP →	+0.101	+2.301	<.001	.002	3	2
SOFT_TISSUE	H2BC1 →	+0.433	+5.977	<.001	.001	3	1
SOFT_TISSUE	H2AC1 →	+0.193	+5.977	<.001	.001	3	1
SOFT_TISSUE	KRTAP10-1 →	+0.034	+5.369	.002	.004	3	1
SOFT_TISSUE	GAGE12E →	+0.090	+4.930	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 374 associations by consensus.

CST9 by SYT10 expression — BLOOD_Myeloma

Explore this box plot interactively →