SYT1

Across TCGA patient cohorts, SYT1 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,762 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SYT1-associated proteins across cancer lineages are HK2, ARFGEF3, and NAXE. Each is linked with SYT1 in more than 3 cancer types. Because this analysis shows association rather than direction, both SYT1-to-partner and partner-to-SYT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SYT1 versus HK2 in BRCA, with a Pearson correlation of -0.33.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SYT1→partner) and Y-score (partner→SYT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	HK2 →	-0.591	-1.690	<.001	<.001	3	4
HNSC	ARFGEF3 →	+0.713	+1.366	<.001	<.001	3	4
UCEC	NAXE →	+0.332	+1.444	.001	<.001	3	4
GBM	PTPN7 →	-0.442	-1.701	<.001	.001	3	4
UCEC	PURA →	+0.347	+1.088	<.001	.001	3	4
HNSC	ZKSCAN1 →	+0.414	+1.291	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,762 associations by consensus.

SYT1 vs HK2 — BRCA

Explore this scatter interactively →