SYT1

Across TCGA patient cohorts, SYT1 protein abundance is significantly associated with the RNA expression of many other genes, with 6,761 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SYT1-associated genes across cancer lineages are RBM11, POU6F2, and RUNDC3A. Each is linked with SYT1 in more than 3 cancer types. Because this analysis shows association rather than direction, both SYT1-to-partner and partner-to-SYT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SYT1 versus RBM11 in BRCA, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SYT1→partner) and Y-score (partner→SYT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RBM11 →	+1.291	+1.161	<.001	<.001	3	4
HNSC	POU6F2 →	+1.532	+1.100	<.001	<.001	3	3
GBM	RUNDC3A →	+1.273	+0.830	<.001	<.001	3	3
LSCC	HTR2C →	+1.014	+0.782	<.001	<.001	3	3
HNSC	DYNC1I1 →	+1.600	+0.824	.001	.009	3	3
GBM	ELAPOR2 →	+1.005	+0.571	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,761 associations by consensus.

SYT1 vs RBM11 — BRCA

Explore this scatter interactively →