Across TCGA patient cohorts, SYS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,534 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible SYS1-associated proteins across cancer lineages are RTF2, MOCS3, and PCIF1. Each is linked with SYS1 in more than 7 cancer types. Because this analysis shows association rather than direction, both SYS1-to-partner and partner-to-SYS1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SYS1→partner) and Y-score (partner→SYS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RTF2 →	+0.321	+0.458	<.001	<.001	3	8
BRCA	MOCS3 →	+0.341	+0.548	<.001	<.001	3	7
OV	PCIF1 →	+0.398	+0.665	<.001	<.001	3	6
GBM	IFT52 →	+0.375	+0.344	<.001	<.001	3	5
OV	NCOA5 →	+0.210	+0.418	<.001	<.001	3	5
COAD	YWHAB →	+0.324	+0.492	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,534 associations by consensus.

Exploration

SYS1 survival (RNA) · tumor vs normal (RNA) · all SYS1 data types