Across TCGA patient cohorts, SYS1 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. COAD shows the largest number of these associations.

The most reproducible SYS1-associated genes across cancer lineages are Neutrophils, naive B-cells, and Fibroblasts. Each is linked with SYS1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SYS1-to-partner and partner-to-SYS1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SYS1→partner) and Y-score (partner→SYS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	Neutrophils →	+0.007	+4.121	.003	.028	3	1
LIHC	naive B-cells →	+0.026	+4.237	.006	.025	3	1
COAD	Fibroblasts →	+0.025	+5.721	.044	.036	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Exploration

SYS1 survival (RNA) · tumor vs normal (RNA) · all SYS1 data types