Across TCGA cell cohorts, SYS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,124 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible SYS1-associated GO terms across cancer lineages are Golgi to plasma membrane protein transport, Establishment of protein localization to membrane, and Mitotic centrosome separation. Each is linked with SYS1 in more than 13 cancer types. Because this analysis shows association rather than direction, both SYS1-to-partner and partner-to-SYS1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SYS1→partner) and Y-score (partner→SYS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Golgi to plasma membrane protein transport →	+0.102	+0.534	.009	.007	2	14
UPPER_AERODIGESTIVE_TRACT	Establishment of protein localization to membrane →	+0.063	+0.792	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Mitotic centrosome separation →	+0.136	+0.830	<.001	<.001	3	12
STOMACH	Negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway →	+0.150	+1.017	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Regulation of mRNA splicing, via spliceosome →	+0.093	+0.884	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Protein linear deubiquitination →	+0.079	+0.726	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,124 associations by consensus.

Exploration

SYS1 survival (RNA) · tumor vs normal (RNA) · all SYS1 data types