SYP

Across TCGA cell cohorts, SYP RNA expression is significantly associated with the go_rna of many other GO terms, with 4,656 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SYP-associated GO terms across cancer lineages are Positive regulation of transmembrane transport, Regulation of potassium ion transport, and Regulation of body fluid levels. Each is linked with SYP in more than 12 cancer types. Because this analysis shows association rather than direction, both SYP-to-partner and partner-to-SYP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of transmembrane transport grouped by SYP-low versus SYP-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SYP→partner) and Y-score (partner→SYP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Positive regulation of transmembrane transport →	-0.092	-2.405	<.001	<.001	3	13
BONE	Regulation of potassium ion transport →	-0.137	-2.507	.001	<.001	3	12
OESOPHAGUS	Regulation of body fluid levels →	-0.097	-1.215	<.001	.001	3	11
BONE	Cell-substrate adhesion →	-0.160	-1.704	<.001	<.001	3	11
BONE	Positive regulation of monoatomic ion transport →	-0.115	-2.038	<.001	<.001	3	11
BONE	Positive regulation of cation transmembrane transport →	-0.089	-1.814	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,656 associations by consensus.

Positive regulation of transmembrane transport by SYP expression — BONE

Explore this box plot interactively →