SYNRG

Across TCGA patient cohorts, SYNRG RNA expression is significantly associated with the protein abundance of many other proteins, with 14,500 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SYNRG-associated proteins across cancer lineages are TAF15, HNRNPLL, and GIT1. Each is linked with SYNRG in more than 4 cancer types. Because this analysis shows association rather than direction, both SYNRG-to-partner and partner-to-SYNRG results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SYNRG versus TAF15 in GBM, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SYNRG→partner) and Y-score (partner→SYNRG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TAF15 →	+0.400	+0.342	<.001	<.001	3	5
GBM	HNRNPLL →	+0.249	+0.368	<.001	<.001	3	5
BRCA	GIT1 →	+0.234	+0.508	<.001	<.001	3	5
LUAD	RPL26 →	-0.546	-0.419	.004	<.001	3	4
GBM	RPS6 →	-0.437	-0.267	.002	.003	3	4
PDAC	RPS6_S240 →	-0.617	-0.265	.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,500 associations by consensus.

SYNRG vs TAF15 — GBM

Explore this scatter interactively →