SYNRG

Across TCGA patient cohorts, SYNRG protein abundance is significantly associated with the RNA expression of many other genes, with 11,170 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible SYNRG-associated genes across cancer lineages are FN1, LOXL2, and AEBP1. Each is linked with SYNRG in more than 6 cancer types. Because this analysis shows association rather than direction, both SYNRG-to-partner and partner-to-SYNRG results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SYNRG versus FN1 in COAD, with a Pearson correlation of -0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SYNRG→partner) and Y-score (partner→SYNRG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	FN1 →	-1.813	-0.206	<.001	.001	3	7
PDAC	LOXL2 →	-1.019	-0.196	<.001	<.001	3	7
CCRCC	AEBP1 →	-1.048	-0.126	<.001	.001	3	6
GBM	PMP22 →	-0.717	-0.205	<.001	<.001	3	6
BRCA	MFAP2 →	-1.119	-0.277	<.001	<.001	3	6
COAD	CALD1 →	-1.071	-0.229	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,170 associations by consensus.

SYNRG vs FN1 — COAD

Explore this scatter interactively →