SYNPR

Across TCGA cell cohorts, SYNPR RNA expression is significantly associated with the RNA expression of many other genes, with 4,443 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SYNPR-associated genes across cancer lineages are IER3, RBM11, and CAMKV. Each is linked with SYNPR in more than 3 cancer types. Because this analysis shows association rather than direction, both SYNPR-to-partner and partner-to-SYNPR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SYNPR versus IER3 in LUNG_SCLC, with a Pearson correlation of -0.46.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SYNPR→partner) and Y-score (partner→SYNPR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	IER3 →	-2.834	-1.786	<.001	<.001	3	4
BONE	RBM11 →	+4.571	+2.355	<.001	<.001	3	3
LUNG_SCLC	CAMKV →	+2.888	+1.553	<.001	<.001	3	3
BONE	AMER2 →	+4.338	+3.158	<.001	<.001	3	3
BONE	TOMM20 →	+0.862	+2.092	<.001	<.001	3	3
BONE	SV2B →	+1.624	+2.388	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,443 associations by consensus.

SYNPR vs IER3 — LUNG_SCLC

Explore this scatter interactively →