SYNGR4

Across TCGA patient cohorts, SYNGR4 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,958 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible SYNGR4-associated GO terms across cancer lineages are DNA replication-dependent chromatin assembly, Double-strand break repair via break-induced replication, and Homologous chromosome pairing at meiosis. Each is linked with SYNGR4 in more than 20 cancer types. Because this analysis shows association rather than direction, both SYNGR4-to-partner and partner-to-SYNGR4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA replication-dependent chromatin assembly grouped by SYNGR4-low versus SYNGR4-high in SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SYNGR4→partner) and Y-score (partner→SYNGR4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	DNA replication-dependent chromatin assembly →	+0.176	+1.615	<.001	<.001	3	21
ACC	Double-strand break repair via break-induced replication →	+0.105	+0.620	<.001	<.001	3	20
ACC	Homologous chromosome pairing at meiosis →	+0.042	+0.464	<.001	<.001	3	19
KICH	Regulation of meiotic cell cycle phase transition →	+0.096	+0.228	<.001	.002	3	19
STAD	CENP-A containing chromatin assembly →	+0.091	+0.587	<.001	<.001	3	18
ACC	G2/MI transition of meiotic cell cycle →	+0.135	+0.619	<.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,958 associations by consensus.

DNA replication-dependent chromatin assembly by SYNGR4 expression — SCLC

Explore this box plot interactively →