SYNGR4

Across TCGA patient cohorts, SYNGR4 protein abundance is significantly associated with the RNA expression of many other genes, with 7,406 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SYNGR4-associated genes across cancer lineages are SCARA3, CLU, and MYLK. Each is linked with SYNGR4 in more than 4 cancer types. Because this analysis shows association rather than direction, both SYNGR4-to-partner and partner-to-SYNGR4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SYNGR4 versus SCARA3 in BRCA, with a Pearson correlation of 0.56.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SYNGR4→partner) and Y-score (partner→SYNGR4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SCARA3 →	+1.734	+0.518	.001	.003	3	5
LUAD	CLU →	+1.788	+0.578	.003	<.001	3	3
LUAD	MYLK →	+0.772	+0.352	.002	.002	3	3
HNSC	RPL7L1P12 →	-1.230	-0.969	.003	.008	3	2
LUAD	FOXC1 →	+1.282	+0.513	.001	<.001	3	2
LUAD	TRIM35 →	+0.437	+0.372	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,406 associations by consensus.

SYNGR4 vs SCARA3 — BRCA

Explore this scatter interactively →