SYNGR4

Across TCGA patient cohorts, SYNGR4 mutation is significantly associated with the RNA expression of many other genes, with 1,042 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SYNGR4-associated genes across cancer lineages are RNU2-24P, RN7SL74P, and OR8B12. Each is linked with SYNGR4 in more than 1 cancer types. Because this analysis shows association rather than direction, both SYNGR4-to-partner and partner-to-SYNGR4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU2-24P grouped by SYNGR4-low versus SYNGR4-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SYNGR4→partner) and Y-score (partner→SYNGR4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RNU2-24P →	+0.221	+3.458	.001	.003	3	2
SKCM	RN7SL74P →	+0.207	+4.452	<.001	<.001	3	2
BRCA	OR8B12 →	+0.170	+5.347	<.001	.006	3	2
BRCA	RNA5SP516 →	+0.578	+7.471	<.001	.008	3	2
BRCA	MIR1263 →	+0.183	+7.471	<.001	.008	3	2
BRCA	RPS3AP1 →	+0.115	+5.540	.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,042 associations by consensus.

RNU2-24P by SYNGR4 expression — SKCM

Explore this box plot interactively →