SYNGR3

Across TCGA patient cohorts, SYNGR3 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,458 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SYNGR3-associated proteins across cancer lineages are ACOT7, KCNAB2_S9, and BASP1_T36. Each is linked with SYNGR3 in more than 4 cancer types. Because this analysis shows association rather than direction, both SYNGR3-to-partner and partner-to-SYNGR3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SYNGR3 versus ACOT7 in GBM, with a Pearson correlation of 0.57.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SYNGR3→partner) and Y-score (partner→SYNGR3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ACOT7 →	+0.400	+1.326	<.001	<.001	3	5
GBM	KCNAB2_S9 →	+0.571	+1.047	<.001	<.001	3	4
GBM	BASP1_T36 →	+0.859	+1.327	<.001	<.001	3	4
CCRCC	BIN3 →	-0.308	-0.311	.001	.005	3	4
GBM	CARMIL2_S1381 →	+0.915	+1.059	<.001	<.001	3	4
BRCA	OGFR →	+0.272	+0.684	.001	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,458 associations by consensus.

SYNGR3 vs ACOT7 — GBM

Explore this scatter interactively →