SYNGR3

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SYNGR3 protein abundance is significantly associated with the RNA expression of many other genes, with 6,982 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SYNGR3-associated genes across cancer lineages are GALNT16, CHRDL1, and RERGL. Each is linked with SYNGR3 in more than 1 cancer types. Because this analysis shows association rather than direction, both SYNGR3-to-partner and partner-to-SYNGR3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SYNGR3 versus GALNT16 in GBM, with a Pearson correlation of 0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SYNGR3→partner) and Y-score (partner→SYNGR3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMGALNT16 →+0.597+0.933<.001<.00132
COADCHRDL1 →+1.952+1.419.004.00132
COADRERGL →+1.180+1.910.005.00132
GBMFAM184A →+0.655+0.977<.001<.00132
COADECRG4 →+1.103+1.608<.001<.00132
GBMDACH2 →+0.698+1.178<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 6,982 associations by consensus.

SYNGR3 vs GALNT16 — GBM

Per-sample scatter of SYNGR3 vs GALNT16 in GBM (Pearson r = 0.46).

Explore this scatter interactively →

Exploration