SYNGR3

Across TCGA cell cohorts, SYNGR3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,254 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SYNGR3-associated GO terms across cancer lineages are Regulation of synaptic vesicle priming, ATP metabolic process, and Regulation of neurotransmitter uptake. Each is linked with SYNGR3 in more than 8 cancer types. Because this analysis shows association rather than direction, both SYNGR3-to-partner and partner-to-SYNGR3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of synaptic vesicle priming grouped by SYNGR3-low versus SYNGR3-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SYNGR3→partner) and Y-score (partner→SYNGR3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Regulation of synaptic vesicle priming →	+0.106	+1.806	<.001	<.001	3	8
LUNG_NSCLC_LUAD	ATP metabolic process →	+0.078	+1.343	<.001	<.001	3	8
URINARY_TRACT	Regulation of neurotransmitter uptake →	-0.175	-1.142	.002	.002	3	8
LUNG_NSCLC_LUAD	Ribonucleoside triphosphate biosynthetic process →	+0.083	+1.532	<.001	<.001	3	8
LUNG_NSCLC_LUAD	Purine nucleoside triphosphate biosynthetic process →	+0.085	+1.523	<.001	<.001	3	8
LUNG_NSCLC_LUAD	Purine ribonucleoside triphosphate biosynthetic process →	+0.085	+1.523	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,254 associations by consensus.

Regulation of synaptic vesicle priming by SYNGR3 expression — OVARY

Explore this box plot interactively →