SYNGR2

Across TCGA patient cohorts, SYNGR2 protein abundance is significantly associated with the RNA expression of many other genes, with 15,190 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SYNGR2-associated genes across cancer lineages are MEIS1, SYDE1, and SLC39A11. Each is linked with SYNGR2 in more than 4 cancer types. Because this analysis shows association rather than direction, both SYNGR2-to-partner and partner-to-SYNGR2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SYNGR2 versus MEIS1 in COAD, with a Pearson correlation of -0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SYNGR2→partner) and Y-score (partner→SYNGR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	MEIS1 →	-0.821	-0.352	<.001	<.001	3	5
CCRCC	SYDE1 →	-0.608	-0.353	<.001	<.001	3	4
BRCA	SLC39A11 →	+0.753	+0.472	<.001	<.001	3	4
GBM	NREP →	-0.784	-0.591	<.001	<.001	3	4
GBM	SHF →	-0.764	-0.499	<.001	<.001	3	4
BRCA	MFGE8 →	-0.876	-0.415	.002	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,190 associations by consensus.

SYNGR2 vs MEIS1 — COAD

Explore this scatter interactively →