SYNGR2

Across TCGA patient cohorts, SYNGR2 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SYNGR2-associated genes across cancer lineages are lymphatic Endothelial cells, Th2 cells, and Macrophages M2. Each is linked with SYNGR2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SYNGR2-to-partner and partner-to-SYNGR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, lymphatic Endothelial cells grouped by SYNGR2-low versus SYNGR2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SYNGR2→partner) and Y-score (partner→SYNGR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	lymphatic Endothelial cells →	-0.024	-3.138	.044	.019	3	1
UCEC	Th2 cells →	+0.208	+2.815	.021	.036	3	1
UCEC	Macrophages M2 →	+0.015	+2.439	.003	.017	1	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

lymphatic Endothelial cells by SYNGR2 expression — UCEC

Explore this box plot interactively →