SYNGR1

Across TCGA patient cohorts, SYNGR1 protein abundance is significantly associated with the RNA expression of many other genes, with 10,126 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SYNGR1-associated genes across cancer lineages are MGAT3, MDH1, and MAPKAPK2. Each is linked with SYNGR1 in more than 3 cancer types. Because this analysis shows association rather than direction, both SYNGR1-to-partner and partner-to-SYNGR1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SYNGR1 versus MGAT3 in LUAD, with a Pearson correlation of 0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SYNGR1→partner) and Y-score (partner→SYNGR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	MGAT3 →	+1.034	+0.453	<.001	<.001	3	4
GBM	MDH1 →	+0.419	+1.222	<.001	<.001	3	3
BRCA	MAPKAPK2 →	-0.556	-0.540	<.001	<.001	3	3
CCRCC	HSD3B7 →	-0.582	-0.443	.001	.001	3	3
GBM	PLPPR4 →	+0.834	+0.848	<.001	<.001	3	3
BRCA	CHPF2 →	-0.625	-0.522	.001	.006	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,126 associations by consensus.

SYNGR1 vs MGAT3 — LUAD

Explore this scatter interactively →