SYNGR1

Across TCGA cell cohorts, SYNGR1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,789 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible SYNGR1-associated GO terms across cancer lineages are Synaptic vesicle membrane organization, Regulation of short-term neuronal synaptic plasticity, and Purine nucleoside triphosphate biosynthetic process. Each is linked with SYNGR1 in more than 10 cancer types. Because this analysis shows association rather than direction, both SYNGR1-to-partner and partner-to-SYNGR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Synaptic vesicle membrane organization grouped by SYNGR1-low versus SYNGR1-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SYNGR1→partner) and Y-score (partner→SYNGR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Synaptic vesicle membrane organization →	+0.154	+1.949	<.001	<.001	3	11
LUNG_SCLC	Regulation of short-term neuronal synaptic plasticity →	+0.127	+1.234	<.001	<.001	3	10
LUNG_SCLC	Purine nucleoside triphosphate biosynthetic process →	+0.096	+2.202	<.001	<.001	3	10
LUNG_SCLC	Purine ribonucleoside triphosphate biosynthetic process →	+0.096	+2.202	<.001	<.001	3	10
LUNG_SCLC	tRNA transcription →	+0.076	+1.923	.009	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Proton motive force-driven ATP synthesis →	+0.085	+1.491	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,789 associations by consensus.

Synaptic vesicle membrane organization by SYNGR1 expression — SKIN

Explore this box plot interactively →