SYNE2

Across TCGA patient cohorts, SYNE2 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,922 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SYNE2-associated proteins across cancer lineages are SYNE2_S4108, UBR7, and MIDEAS. Each is linked with SYNE2 in more than 5 cancer types. Because this analysis shows association rather than direction, both SYNE2-to-partner and partner-to-SYNE2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SYNE2 versus SYNE2_S4108 in GBM, with a Pearson correlation of 0.73.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SYNE2→partner) and Y-score (partner→SYNE2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SYNE2_S4108 →	+0.695	+0.813	<.001	<.001	3	6
GBM	UBR7 →	+0.356	+0.546	<.001	<.001	3	6
HNSC	MIDEAS →	+0.230	+0.952	<.001	<.001	3	6
GBM	DNTTIP1 →	+0.361	+0.648	<.001	.001	3	6
GBM	MTA1 →	+0.424	+0.705	<.001	<.001	3	5
LSCC	TRMT5 →	+0.360	+0.579	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,922 associations by consensus.

SYNE2 vs SYNE2_S4108 — GBM

Explore this scatter interactively →