SYNE1

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SYNE1 RNA expression is significantly associated with the protein abundance of many other proteins, with 24,270 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SYNE1-associated proteins across cancer lineages are TLN1, PARVA, and PDLIM7. Each is linked with SYNE1 in more than 8 cancer types. Because this analysis shows association rather than direction, both SYNE1-to-partner and partner-to-SYNE1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SYNE1 versus TLN1 in UCEC, with a Pearson correlation of 0.58.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SYNE1→partner) and Y-score (partner→SYNE1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECTLN1 →+0.480+0.835<.001<.00139
UCECPARVA →+0.602+0.851<.001<.00139
UCECPDLIM7 →+0.749+0.911<.001<.00139
OVPRKG1 →+0.771+0.924<.001<.00139
UCECRSU1 →+0.493+0.884<.001<.00139
UCECFERMT2 →+0.609+0.789<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 24,270 associations by consensus.

SYNE1 vs TLN1 — UCEC

Per-sample scatter of SYNE1 vs TLN1 in UCEC (Pearson r = 0.58).

Explore this scatter interactively →

Exploration