SYNCRIP

Across TCGA patient cohorts, SYNCRIP protein abundance is significantly associated with the RNA expression of many other genes, with 20,398 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SYNCRIP-associated genes across cancer lineages are RNGTT, ZBTB24, and CASP8AP2. Each is linked with SYNCRIP in more than 6 cancer types. Because this analysis shows association rather than direction, both SYNCRIP-to-partner and partner-to-SYNCRIP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SYNCRIP versus RNGTT in LSCC, with a Pearson correlation of 0.70.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SYNCRIP→partner) and Y-score (partner→SYNCRIP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RNGTT →	+0.416	+0.302	<.001	<.001	3	7
CCRCC	ZBTB24 →	+0.400	+0.190	<.001	<.001	3	7
LSCC	CASP8AP2 →	+0.552	+0.248	<.001	<.001	3	7
BRCA	QRSL1 →	+0.494	+0.321	.001	.002	3	7
LSCC	ORC3 →	+0.592	+0.328	<.001	<.001	3	7
UCEC	LTV1 →	+0.899	+0.290	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,398 associations by consensus.

SYNCRIP vs RNGTT — LSCC

Explore this scatter interactively →