SYNCRIP

Across TCGA cell cohorts, SYNCRIP RNA expression is significantly associated with the go_rna of many other GO terms, with 3,930 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SYNCRIP-associated GO terms across cancer lineages are DNA-templated DNA replication, Spermine biosynthetic process, and Spermidine biosynthetic process. Each is linked with SYNCRIP in more than 19 cancer types. Because this analysis shows association rather than direction, both SYNCRIP-to-partner and partner-to-SYNCRIP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA-templated DNA replication grouped by SYNCRIP-low versus SYNCRIP-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SYNCRIP→partner) and Y-score (partner→SYNCRIP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	DNA-templated DNA replication →	+0.113	+0.801	<.001	.001	3	20
BREAST	Spermine biosynthetic process →	+0.218	+1.014	<.001	<.001	3	20
BREAST	Spermidine biosynthetic process →	+0.216	+0.948	<.001	<.001	3	19
SOFT_TISSUE	Replication fork processing →	+0.114	+0.860	<.001	<.001	3	19
OVARY	Protein localization to kinetochore →	+0.164	+1.170	<.001	<.001	3	19
SOFT_TISSUE	DNA replication →	+0.108	+0.874	<.001	<.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,930 associations by consensus.

DNA-templated DNA replication by SYNCRIP expression — PANCREAS

Explore this box plot interactively →