SYNC

Across TCGA cell cohorts, SYNC RNA expression is significantly associated with the go_rna of many other GO terms, with 5,352 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SYNC-associated GO terms across cancer lineages are Transport of virus, Intracellular transport of virus, and Skeletal muscle fiber development. Each is linked with SYNC in more than 11 cancer types. Because this analysis shows association rather than direction, both SYNC-to-partner and partner-to-SYNC results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Transport of virus grouped by SYNC-low versus SYNC-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SYNC→partner) and Y-score (partner→SYNC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Transport of virus →	+0.259	+2.344	<.001	.003	3	12
LUNG_NSCLC_LUSC	Intracellular transport of virus →	+0.259	+2.344	<.001	.003	3	12
LIVER	Skeletal muscle fiber development →	+0.216	+2.626	<.001	<.001	3	12
BONE	Positive regulation of stress fiber assembly →	+0.183	+3.115	<.001	<.001	3	12
BONE	Negative regulation of amino acid biosynthetic process →	+0.306	+2.604	<.001	<.001	3	12
BONE	Negative regulation of amino acid metabolic process →	+0.306	+2.604	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,352 associations by consensus.

Transport of virus by SYNC expression — LUNG_NSCLC_LUSC

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