Across TCGA patient cohorts, SYN3 protein abundance is significantly associated with the RNA expression of many other genes, with 4,283 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SYN3-associated genes across cancer lineages are CRHR1, YPEL1, and SNRPD3. Each is linked with SYN3 in more than 1 cancer types. Because this analysis shows association rather than direction, both SYN3-to-partner and partner-to-SYN3 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SYN3→partner) and Y-score (partner→SYN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CRHR1 →	+0.155	+0.881	<.001	<.001	3	2
GBM	YPEL1 →	+0.455	+0.514	.009	.006	3	1
GBM	SNRPD3 →	+0.411	+0.621	<.001	<.001	3	1
GBM	PRODH →	+0.806	+0.661	<.001	<.001	3	1
GBM	GRK3 →	+0.363	+0.502	.001	<.001	3	1
GBM	SEZ6L →	+1.834	+0.604	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,283 associations by consensus.

Exploration

SYN3 survival (RNA) · tumor vs normal (RNA) · all SYN3 data types