Across TCGA cell cohorts, SYN3 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,713 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible SYN3-associated GO terms across cancer lineages are Negative regulation of calcium ion export across plasma membrane, ERAD pathway, and Negative regulation of membrane protein ectodomain proteolysis. Each is linked with SYN3 in more than 4 cancer types. Because this analysis shows association rather than direction, both SYN3-to-partner and partner-to-SYN3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SYN3→partner) and Y-score (partner→SYN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Negative regulation of calcium ion export across plasma membrane →	+0.058	+0.991	.002	.001	3	5
LUNG_NSCLC_LUAD	ERAD pathway →	+0.037	+0.176	.001	.002	3	5
SKIN	Negative regulation of membrane protein ectodomain proteolysis →	+0.178	+1.331	<.001	<.001	3	5
OVARY	DNA-templated transcription initiation →	+0.051	+0.385	.003	.005	3	5
LUNG_SCLC	Nucleic acid catabolic process →	+0.048	+1.492	<.001	.002	3	5
LUNG_SCLC	Negative regulation of mRNA metabolic process →	+0.038	+0.963	.009	.004	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,713 associations by consensus.

Exploration

SYN3 survival (RNA) · tumor vs normal (RNA) · all SYN3 data types