SYN2

Across TCGA patient cohorts, SYN2 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,404 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SYN2-associated proteins across cancer lineages are SPTBN1, PSME2, and LRRFIP1. Each is linked with SYN2 in more than 4 cancer types. Because this analysis shows association rather than direction, both SYN2-to-partner and partner-to-SYN2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SYN2 versus SPTBN1 in PDAC, with a Pearson correlation of 0.29.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SYN2→partner) and Y-score (partner→SYN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	SPTBN1 →	+0.343	+0.607	<.001	<.001	3	5
GBM	PSME2 →	-0.284	-1.119	<.001	<.001	3	4
BRCA	LRRFIP1 →	-0.343	-0.828	.001	.001	3	4
UCEC	GMPPB →	-0.370	-1.300	<.001	.003	3	4
GBM	RBM47 →	-0.475	-1.119	<.001	<.001	3	3
LSCC	TBCD →	+0.293	+0.979	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,404 associations by consensus.

SYN2 vs SPTBN1 — PDAC

Explore this scatter interactively →