SYN2

Across TCGA patient cohorts, SYN2 protein abundance is significantly associated with the RNA expression of many other genes, with 6,977 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SYN2-associated genes across cancer lineages are DYNC1I1, UNC13C, and PI16. Each is linked with SYN2 in more than 3 cancer types. Because this analysis shows association rather than direction, both SYN2-to-partner and partner-to-SYN2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SYN2 versus DYNC1I1 in UCEC, with a Pearson correlation of 0.63.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SYN2→partner) and Y-score (partner→SYN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	DYNC1I1 →	+2.928	+1.254	<.001	<.001	3	4
GBM	UNC13C →	+1.517	+1.229	<.001	<.001	3	3
LUAD	PI16 →	+2.131	+0.635	.001	.001	3	3
GBM	OPRM1 →	+0.346	+1.095	<.001	<.001	3	3
BRCA	TMCC2 →	+1.919	+1.447	<.001	<.001	3	3
UCEC	EPHA7 →	+2.210	+0.915	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,977 associations by consensus.

SYN2 vs DYNC1I1 — UCEC

Explore this scatter interactively →