SYN2

Across TCGA cell cohorts, SYN2 protein abundance is significantly associated with the RNA expression of many other genes, with 893 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible SYN2-associated genes across cancer lineages are MAGED1, NDFIP1, and DHX36. Each is linked with SYN2 in more than 3 cancer types. Because this analysis shows association rather than direction, both SYN2-to-partner and partner-to-SYN2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SYN2 versus MAGED1 in CNS, with a Pearson correlation of -0.57.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SYN2→partner) and Y-score (partner→SYN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	MAGED1 →	-1.227	-1.878	.003	.003	3	3
URINARY_TRACT	NDFIP1 →	+0.626	+1.160	.002	.002	3	3
STOMACH	DHX36 →	+0.997	+1.700	<.001	.008	3	3
STOMACH	NOL4L →	+1.092	+1.002	<.001	.006	3	3
STOMACH	NCOA4 →	+0.606	+1.002	<.001	.006	3	3
STOMACH	LSG1 →	+1.365	+1.507	.001	.008	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 893 associations by consensus.

SYN2 vs MAGED1 — CNS

Explore this scatter interactively →