SYN1

Across TCGA patient cohorts, SYN1 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,663 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SYN1-associated proteins across cancer lineages are AP3B2_S735, SRA1, and TRIP11. Each is linked with SYN1 in more than 3 cancer types. Because this analysis shows association rather than direction, both SYN1-to-partner and partner-to-SYN1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SYN1 versus AP3B2_S735 in BRCA, with a Pearson correlation of 0.60.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SYN1→partner) and Y-score (partner→SYN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	AP3B2_S735 →	+2.225	+1.336	.001	.001	3	4
GBM	SRA1 →	-0.208	-1.524	<.001	<.001	3	3
COAD	TRIP11 →	-0.164	-0.335	.004	.003	3	3
BRCA	SCG2 →	+1.418	+1.331	.007	.008	3	3
GBM	CASP7 →	-0.440	-0.871	<.001	.001	3	3
BRCA	CPLX2 →	+2.566	+1.588	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,663 associations by consensus.

SYN1 vs AP3B2_S735 — BRCA

Explore this scatter interactively →