SYN1

Across TCGA patient cohorts, SYN1 protein abundance is significantly associated with the RNA expression of many other genes, with 9,753 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SYN1-associated genes across cancer lineages are SNAP25, SYT4, and BEX1. Each is linked with SYN1 in more than 3 cancer types. Because this analysis shows association rather than direction, both SYN1-to-partner and partner-to-SYN1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SYN1 versus SNAP25 in BRCA, with a Pearson correlation of 0.70.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SYN1→partner) and Y-score (partner→SYN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SNAP25 →	+3.350	+2.475	<.001	<.001	3	4
BRCA	SYT4 →	+2.552	+1.645	<.001	<.001	3	4
BRCA	BEX1 →	+3.499	+1.714	.001	.001	3	4
GBM	KCNB1 →	+0.963	+0.632	<.001	<.001	3	4
GBM	ANKS1B →	+1.365	+0.721	<.001	<.001	3	4
HNSC	CLDN5 →	+1.550	+1.022	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,753 associations by consensus.

SYN1 vs SNAP25 — BRCA

Explore this scatter interactively →