SYF2

Across TCGA patient cohorts, SYF2 protein abundance is significantly associated with the protein abundance of many other proteins, with 20,025 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SYF2-associated proteins across cancer lineages are SNRPA1, PPP1R8, and RBBP4. Each is linked with SYF2 in more than 9 cancer types. Because this analysis shows association rather than direction, both SYF2-to-partner and partner-to-SYF2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SYF2 versus SNRPA1 in GBM, with a Pearson correlation of 0.60.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SYF2→partner) and Y-score (partner→SYF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SNRPA1 →	+0.351	+0.337	<.001	<.001	3	10
GBM	PPP1R8 →	+0.232	+0.346	<.001	<.001	3	9
BRCA	RBBP4 →	+0.435	+0.476	<.001	<.001	3	9
GBM	DDX17 →	+0.317	+0.295	<.001	<.001	3	9
GBM	SF3B2 →	+0.291	+0.312	<.001	<.001	3	9
GBM	HNRNPK →	+0.263	+0.323	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,025 associations by consensus.

SYF2 vs SNRPA1 — GBM

Explore this scatter interactively →