SYF2

Across TCGA cell cohorts, SYF2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,212 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible SYF2-associated GO terms across cancer lineages are DNA replication proofreading, Positive regulation of mitochondrial electron transport, NADH to ubiquinone, and UDP biosynthetic process. Each is linked with SYF2 in more than 10 cancer types. Because this analysis shows association rather than direction, both SYF2-to-partner and partner-to-SYF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA replication proofreading grouped by SYF2-low versus SYF2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SYF2→partner) and Y-score (partner→SYF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	DNA replication proofreading →	-0.225	-0.474	.001	.001	3	11
SOFT_TISSUE	Positive regulation of mitochondrial electron transport, NADH to ubiquinone →	+0.121	+0.466	.001	.008	3	10
BLOOD_Leukemia	UDP biosynthetic process →	-0.080	-0.547	<.001	<.001	3	10
BLOOD_Leukemia	Pyrimidine ribonucleoside diphosphate biosynthetic process →	-0.080	-0.547	<.001	<.001	3	10
SKIN	Neutrophil degranulation →	+0.159	+0.377	.001	.005	3	9
URINARY_TRACT	Pyrimidine nucleoside diphosphate biosynthetic process →	-0.145	-0.590	.001	.006	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,212 associations by consensus.

DNA replication proofreading by SYF2 expression — BONE

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