SYDE2

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SYDE2 protein abundance is significantly associated with the protein abundance of many other proteins, with 6,220 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SYDE2-associated proteins across cancer lineages are SYDE2_S104, SYNPO_S525, and SYNPO_S838. Each is linked with SYDE2 in more than 3 cancer types. Because this analysis shows association rather than direction, both SYDE2-to-partner and partner-to-SYDE2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SYDE2 versus SYDE2_S104 in BRCA, with a Pearson correlation of 0.46.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SYDE2→partner) and Y-score (partner→SYDE2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCASYDE2_S104 →+0.855+0.426.009.00814
BRCASYNPO_S525 →+0.641+0.558<.001<.00132
UCECSYNPO_S838 →+1.150+0.931<.001<.00132
LUADTAF13 →+0.348+0.468<.001<.00132
UCECTNS1_S1446 →+1.196+0.746<.001<.00132
UCECTNS1_S926 →+1.365+1.237<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 6,220 associations by consensus.

SYDE2 vs SYDE2_S104 — BRCA

Per-sample scatter of SYDE2 vs SYDE2_S104 in BRCA (Pearson r = 0.46).

Explore this scatter interactively →

Exploration